IHC image of CSB-PA012906LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA012906LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
LGR5 Antibody
CSB-PA012906LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetLGR5
Overview
- SupplierCusabio
- Product NameLGR5 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8549
- Target nameLGR5
- Target descriptionleucine rich repeat containing G protein-coupled receptor 5
- Target synonymsFEX, GPR49, GPR67, GRP49, HG38, leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, orphan G protein-coupled receptor HG38
- HostRabbit
- IsotypeIgG
- Protein IDO75473
- Protein NameLeucine-rich repeat-containing G-protein coupled receptor 5
- Scientific DescriptionReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
Related products
Product group Antibodies
Lgr5 Recombinant AntibodyCAC12325
ApplicationsFlow Cytometry, Western Blot, ELISA
TargetLGR5
- SizePrice
Product group Antibodies
LGR5 antibodyGTX130204
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetLGR5
- SizePrice
Product group Antibodies
Anti-LgR5 [1-12]AB04170-11.0
ApplicationsFlow Cytometry, ELISA, ImmunoHistoChemistry
TargetLGR5
- SizePrice
Product group Antibodies
Anti-LGR5 Antibody Picoband(r)A00239-2-CARRIER-FREE
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
TargetLGR5
- SizePrice
Product group Antibodies
Anti-LGR5 Antibody144-10545
ApplicationsImmunoFluorescence, Western Blot
TargetLGR5
- SizePrice
Product group Antibodies
ApplicationsWestern Blot, ImmunoCytoChemistry
- SizePrice
Product group Antibodies
GPR49/LGR5 Polyclonal AntibodyBS-20746R
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetLGR5
- SizePrice
