LH1 antibody

GeneTex

LH1 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

PLOD1

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

EDS6, EDSKCL1, LH, LH1, LLH, PLOD, procollagen-lysine,2-oxoglutarate 5-dioxygenase 1, lysine hydroxylase, lysyl hydroxlase 1, procollagen lysyl hydroxylase 1, procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1

Rabbit

IgG

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

-20°C or -80°C,2°C to 8°C

12352203