Lifirafenib

MedChem Express

Lifirafenib [1446090-79-4]

9

1446090-79-4

Research Use Only

98.01

C25H17F3N4O3

478.42

Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively.

O=C1NC2=NC=CC(OC3=CC=C(O[C@@]4([H])[C@]5([H])[C@@H]4C6=NC7=CC=C(C(F)(F)F)C=C7N6)C5=C3)=C2CC1

-20°C,2°C to 8°C

12352200