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Lifirafenib (BGB-283)

M10475
AbMole BioScience
CAS Number1446090-79-4
Product group Chemicals
Molecular Weight478.42
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Lifirafenib (BGB-283)
  • Delivery Days Customer
    9
  • CAS Number
    1446090-79-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C25H17F3N4O3
  • Molecular Weight
    478.42
  • Scientific Description
    Lifirafenib (BGB-283) is a novel potent and selective RAF Kinase and EGFR inhibitor with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
  • SMILES
    FC(F)(F)C1=CC=C2N=C([NH]C2=C1)C3C4OC5=CC=C(OC6=C7CCC(=O)N=C7NC=C6)C=C5C34
  • UNSPSC
    12352200

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