Bio-Connect

LIFR antibody

GTX134466
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetLIFR
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Overview

  • Supplier
    GeneTex
  • Product Name
    LIFR antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.71 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3977
  • Target name
    LIFR
  • Target description
    LIF receptor subunit alpha
  • Target synonyms
    CD118; CD118 antigen; leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha; LIF receptor alpha; LIF-R; SJS2; STWS; SWS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP42702
  • Protein Name
    Leukemia inhibitory factor receptor
  • Scientific Description
    This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203