LIFR antibody
GTX134466
Overview
- SupplierGeneTex
- Product NameLIFR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.71 mg/ml
- ConjugateUnconjugated
- Gene ID3977
- Target nameLIFR
- Target descriptionLIF receptor subunit alpha
- Target synonymsCD118; CD118 antigen; leukemia inhibitory factor receptor; leukemia inhibitory factor receptor alpha; LIF receptor alpha; LIF-R; SJS2; STWS; SWS
- HostRabbit
- IsotypeIgG
- Protein IDP42702
- Protein NameLeukemia inhibitory factor receptor
- Scientific DescriptionThis gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203