Bio-Connect

LILRB1 antibody [GHI/75] (PE)

Research Use Only
GTX00517-08
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetLILRB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    LILRB1 antibody [GHI/75] (PE)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GHI/75
  • Conjugate
    RPE
  • Formulation
    Liquid
  • Gene ID10859
  • Target name
    LILRB1
  • Target description
    leukocyte immunoglobulin like receptor B1
  • Target synonyms
    CD85 antigen-like family member J; CD85J; Ig-like transcript 2; ILT2; ILT-2; immunoglobulin heavy chain variable region; leucocyte Ig-like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LIR1; LIR-1; MIR7; MIR-7; monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ8NHL6
  • Protein Name
    Leukocyte immunoglobulin-like receptor subfamily B member 1
  • Scientific Description
    This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203