Western blot analysis of extracts of various cell lines using LITAF Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using LITAF Polyclonal Antibody at dilution of 1:1000.
LITAF Polyclonal Antibody
E-AB-60978
Product group Antibodies
Overview
- SupplierElabscience
- Product NameLITAF Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionLipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Pagets disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203