LONP1 Antibody

Cusabio

LONP1 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

LONP1

lon peptidase 1, mitochondrial

CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON, lon protease homolog, mitochondrial, hLON ATP-dependent protease, mitochondrial ATP-dependent protease Lon, mitochondrial lon protease-like protein, serine protease 15

Rabbit

IgG

Lon protease homolog, mitochondrial

ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Human

-20°C or -80°C

41116161