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LRIG1 antibody [C2C3], C-term

GTX119485
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetLRIG1
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Overview

  • Supplier
    GeneTex
  • Product Name
    LRIG1 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by customer review data.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.61 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID26018
  • Target name
    LRIG1
  • Target description
    leucine rich repeats and immunoglobulin like domains 1
  • Target synonyms
    leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin-like domains protein 1; LIG1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96JA1
  • Protein Name
    Leucine-rich repeats and immunoglobulin-like domains protein 1
  • Scientific Description
    Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Aryl Hydrocarbon Receptor Defect Attenuates Mitogen-Activated Signaling through Leucine-Rich Repeats and Immunoglobulin-like Domains 1 (LRIG1)-Dependent EGFR Degradation. Hsu HL et al., 2021 Sep 15, Int J Mol Sci
    Read more
  • LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Yokdang N et al., 2016 Jun 2, Oncogene
    Read more