Western Blot Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, HepG2 whole cell lysate All lanes: LRPPRC antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 158 kDa Observed band size: 158 kDa
Western Blot Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, HepG2 whole cell lysate All lanes: LRPPRC antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 158 kDa Observed band size: 158 kDa
LRPPRC Antibody
CSB-PA013105LA01HU
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetLRPPRC
Overview
- SupplierCusabio
- Product NameLRPPRC Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10128
- Target nameLRPPRC
- Target descriptionleucine rich pentatricopeptide repeat containing
- Target synonyms130 kDa leucine-rich protein; CLONE-23970; GP130; leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; LRP 130; LRP130; LSFC; MC4DN5; mitochondrial leucine-rich PPR motif-containing protein
- HostRabbit
- IsotypeIgG
- Protein IDP42704
- Protein NameLeucine-rich PPR motif-containing protein, mitochondrial
- Scientific DescriptionMay play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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