MAPK14 (Ab-182) Antibody

Cusabio

MAPK14 (Ab-182) Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

MAPK14

mitogen-activated protein kinase 14

CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14, CSAID-binding protein, MAP kinase 14, MAP kinase Mxi2, MAP kinase p38 alpha, MAX-interacting protein 2, cytokine suppressive anti-inflammatory drug binding protein, mitogen-activated protein kinase p38 alpha, p38 MAP kinase, p38 mitogen activated protein kinase, p38alpha Exip, stress-activated protein kinase 2A

Rabbit

IgG

Mitogen-activated protein kinase 14

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. Ming Zheng, et al.(2005) The FASEB Journal. 19: 109-111 Bernt van den et al.(2001) Blink Immunology, 166: 582-587 Arshad Rahman, et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024 Osamu Yoshino, et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241

Human, Mouse, Rat

-20°C or -80°C

41116161