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Product group Antibodies
AdipoGen Life Sciences
ApplicationsFunctional Assay, Western Blot, ELISA
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Binding of Progranulin (human) (rec.) (untagged) (Prod. No. AG-40A-0188Y) to Sortilin (human) (rec.) (His) (Prod. No. AG-40B-0229) is inhibited by the antibody Sortilin (human), mAb (rec.) (blocking) [Latozinemab Bioimilar] (Prod. No. AG-27B-7000PF). Methods: Progranulin (human) (rec.) (untagged) is coated on an ELISA plate at 1 microg/ml. Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar] or an unrelated mAb (Control) is added (starting at 20 microg/ml with a twofold serial dilution) together with 250 ng/ml of Sortilin (rec.) (His) for 1 hour. The binding is detected using an anti-His (HRP) incubated for 30 minutes followed by addition of the substrate TMB. The decreasing ODs observed in the Y axis represent the binding between Progranulin and Sortilin that is inhibited in a dose-dependent manner by Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar]. This inhibition is not observed with the control antibody.
Product group Antibodies
AdipoGen Life Sciences
ApplicationsNeutralisation/Blocking
TargetSORT1
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Product group Antibodies
AdipoGen Life Sciences
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Streptavidin (HRP)AG-35B-0014E
Protein IDP22629
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Protein Structure
Product group Antibodies
AdipoGen Life Sciences
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDQ00724
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Specific interaction of human ST2 (Prod. No. AG-40A-0059) with recombinant human IL-33. An indirect competitive ELISA was performed as follows; 1) coat microtiter plate wells with hST2-Fc (10microg/ml); 2) add a varying concentrations of hIL-33 with
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDQ01638
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Adipogenesis inhibition of MSCs. MSCs (Mesenchymal stem cells) were maintained in DMEM, supplemented with 10% fetal bovine serum, penicilin-streptomycin and glutamine. For differentiation of MSCs, MSCs were cultured in adipogenic medium which was gr
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDO00548
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DLL4 (human):Fc (human) (rec.)
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDQ9NR61
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Induction of IL-6 expression in human dermal fibroblasts by Jagged-1 (human):Fc (human) (rec.) (Prod. No. AG-40A-0081). Method: Jagged-1 (human):Fc was coated on a 12-well plate at 1microg/ml overnight at 4°C. Human dermal fibroblasts were cultured in
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDP78504
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Protein IDQ9Y219
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