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Product group Antibodies
ApplicationsFunctional Assay, Western Blot, ELISA
- SizePrice
Product group Antibodies
ApplicationsNeutralisation/Blocking
TargetSORT1
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Product group Proteins / Signaling Molecules
ST2 (human):Fc (human) (rec.)AG-40A-0059
Protein IDQ01638
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Product group Proteins / Signaling Molecules
DLL4 (human):Fc (human) (rec.)AG-40A-0077Y
Protein IDQ9NR61
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Product group Proteins / Signaling Molecules
Jagged-1 (human):Fc (human) (rec.)AG-40A-0081
Protein IDP78504
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Product group Proteins / Signaling Molecules
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Product group Proteins / Signaling Molecules
Jagged-2 (human):Fc (human) (rec.)AG-40A-0155Y
Protein IDQ9Y219
- SizePrice
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Back to overview![Binding of Progranulin (human) (rec.) (untagged) (Prod. No. AG-40A-0188Y) to Sortilin (human) (rec.) (His) (Prod. No. AG-40B-0229) is inhibited by the antibody Sortilin (human), mAb (rec.) (blocking) [Latozinemab Bioimilar] (Prod. No. AG-27B-7000PF). Methods: Progranulin (human) (rec.) (untagged) is coated on an ELISA plate at 1 microg/ml. Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar] or an unrelated mAb (Control) is added (starting at 20 microg/ml with a twofold serial dilution) together with 250 ng/ml of Sortilin (rec.) (His) for 1 hour. The binding is detected using an anti-His (HRP) incubated for 30 minutes followed by addition of the substrate TMB. The decreasing ODs observed in the Y axis represent the binding between Progranulin and Sortilin that is inhibited in a dose-dependent manner by Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar]. This inhibition is not observed with the control antibody.](https://adipogen.com/pub/media/catalog/product/a/g/ag-27b-7000pf-binding_blocking_assay-500px.jpg)




