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The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157
The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157
The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157

MAT2A antibody [AT3A2]

GTX50027
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMAT2A
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Overview

  • Supplier
    GeneTex
  • Product Name
    MAT2A antibody [AT3A2]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Based on the blast result, this antibody may cross-react with human MAT1A.
  • Application Supplier Note
    We recommend the following starting dilutions:Western Blot: Use at 1:1000 ~ 2000.Optimal working concentrations should be determined experimentally by the end user.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AT3A2
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4144
  • Target name
    MAT2A
  • Target description
    methionine adenosyltransferase 2A
  • Target synonyms
    adoMet synthase 2; adoMet synthetase 2; MAT 2; MATA2; MATII; MAT-II; methionine adenosyltransferase 2; methionine adenosyltransferase II, alpha; S-adenosylmethionine synthase isoform type-2; SAMS2; testicular tissue protein Li 121
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP31153
  • Protein Name
    S-adenosylmethionine synthase isoform type-2
  • Scientific Description
    The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Translocation of Methionine Adenosyl Transferase MAT2A and Its Prognostic Relevance for Liver Hepatocellular Carcinoma.
    Read more
  • Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Li JT et al., 2022 Jun 22, Signal Transduct Target Ther
    Read more
  • MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients. Chu PY et al., 2021 May 20, Int J Mol Sci
    Read more
  • Methionine is a metabolic dependency of tumor-initiating cells. Wang Z et al., 2019 May, Nat Med
    Read more