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ProductsBack/MAT2A antibody [AT3A2]
The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157
The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157
The data was published in the 2022 in Signal Transduct Target Ther. PMID: 35729157

MAT2A antibody [AT3A2]

GTX50027
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMAT2A
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Overview

  • Supplier
    GeneTex
  • Product Name
    MAT2A antibody [AT3A2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    We recommend the following starting dilutions:Western Blot: Use at 1:1000 ~ 2000.Optimal working concentrations should be determined experimentally by the end user.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AT3A2
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4144
  • Target name
    MAT2A
  • Target description
    methionine adenosyltransferase 2A
  • Target synonyms
    MATA2, MATII, SAMS2, S-adenosylmethionine synthase isoform type-2, MAT 2, MAT-II, adoMet synthase 2, adoMet synthetase 2, methionine adenosyltransferase 2, methionine adenosyltransferase II, alpha, testicular tissue protein Li 121
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP31153
  • Protein Name
    S-adenosylmethionine synthase isoform type-2
  • Scientific Description
    The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chu PY, Chou DA, Chen PM, et al. Translocation of Methionine Adenosyl Transferase MAT2A and Its Prognostic Relevance for Liver Hepatocellular Carcinoma. Int J Mol Sci. 2023,24(10). doi: 10.3390/ijms24109103
    Read this paper
  • Li JT, Yang H, Lei MZ, et al. Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA. Signal Transduct Target Ther. 2022,7(1):192. doi: 10.1038/s41392-022-01017-8
    Read this paper
  • Chu PY, Wu HJ, Wang SM, et al. MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients. Int J Mol Sci. 2021,22(10). doi: 10.3390/ijms22105382
    Read this paper
  • Wang Z, Yip LY, Lee JHJ, et al. Methionine is a metabolic dependency of tumor-initiating cells. Nat Med. 2019,25(5):825-837. doi: 10.1038/s41591-019-0423-5
    Read this paper

Datasheet

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