![IHC-P analysis of breast tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of breast tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2364_IHC-P_w_23061420_577.webp)
IHC-P analysis of breast tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
MCL1 antibody [10F6]
GTX84140
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMCL1
Overview
- SupplierGeneTex
- Product NameMCL1 antibody [10F6] - Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10F6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4170
- Target nameMCL1
- Target descriptionMCL1 apoptosis regulator, BCL2 family member
- Target synonymsBCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, induced myeloid leukemia cell differentiation protein Mcl-1, BCL2 family apoptosis regulator, MCL1, BCL2 family apoptosis regulator, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, myeloid cell leukemia 1, myeloid cell leukemia ES, myeloid cell leukemia sequence 1 (BCL2-related)
- HostMouse
- IsotypeIgG1
- Protein IDQ07820
- Protein NameInduced myeloid leukemia cell differentiation protein Mcl-1
- Scientific DescriptionInvolved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of liver carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of liver carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2365_IHC-P_w_23061420_615.webp)
![IHC-P analysis of pancreas carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of pancreas carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2366_IHC-P_w_23061420_561.webp)
![IHC-P analysis of prostate carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of prostate carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2367_IHC-P_w_23061420_179.webp)
![IHC-P analysis of kidney tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of kidney tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2368_IHC-P_w_23061420_367.webp)
![IHC-P analysis of prostate tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50 IHC-P analysis of prostate tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2369_IHC-P_w_23061420_815.webp)
![FACS analysis of HEK293T cells transfected with either MCL1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84140 MCL1 antibody [10F6]. FACS analysis of HEK293T cells transfected with either MCL1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84140 MCL1 antibody [10F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_311_FACS_w_23061420_697.webp)
![WB analysis of Jurkat cell lysate using GTX84140 MCL1 antibody [10F6]. Loading : 10 ug per lane Dilution : 1:200 WB analysis of Jurkat cell lysate using GTX84140 MCL1 antibody [10F6]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_3894_WB_w_23061420_843.webp)
![WB analysis of HEK293T cells transfected with MCL1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84140 MCL1 antibody [10F6]. Loading : 5 ug per lane WB analysis of HEK293T cells transfected with MCL1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84140 MCL1 antibody [10F6]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_4138_WB_w_23061420_628.webp)
![ICC/IF analysis of COS7 cells transiently transfected with MCL1 plasmid using GTX84140 MCL1 antibody [10F6]. ICC/IF analysis of COS7 cells transiently transfected with MCL1 plasmid using GTX84140 MCL1 antibody [10F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_959_ICCIF_w_23061420_632.webp)





![IHC-P analysis of kidney tissue using GTX84132 MCL1 antibody [10C5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84132/GTX84132_2362_IHC-P_w_23061420_484.webp)
![FACS analysis of HEK293T cells using GTX84135 MCL1 antibody [2E11]. Black : Cell only Blue : Primary antibody Red : Isotype control antibody](https://www.genetex.com/upload/website/prouct_img/normal/GTX84135/GTX84135_308_FACS_w_23061420_152.webp)
