IHC-P analysis of breast tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
![IHC-P analysis of liver carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2365_IHC-P_w_23061420_615.webp "IHC-P analysis of liver carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of pancreas carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2366_IHC-P_w_23061420_561.webp "IHC-P analysis of pancreas carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of prostate carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2367_IHC-P_w_23061420_179.webp "IHC-P analysis of prostate carcinoma tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of kidney tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2368_IHC-P_w_23061420_367.webp "IHC-P analysis of kidney tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of prostate tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_2369_IHC-P_w_23061420_815.webp "IHC-P analysis of prostate tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![FACS analysis of HEK293T cells transfected with either MCL1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84140 MCL1 antibody [10F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_311_FACS_w_23061420_697.webp "FACS analysis of HEK293T cells transfected with either MCL1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84140 MCL1 antibody [10F6].")
![WB analysis of Jurkat cell lysate using GTX84140 MCL1 antibody [10F6]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_3894_WB_w_23061420_843.webp "WB analysis of Jurkat cell lysate using GTX84140 MCL1 antibody [10F6]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of HEK293T cells transfected with MCL1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84140 MCL1 antibody [10F6]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_4138_WB_w_23061420_628.webp "WB analysis of HEK293T cells transfected with MCL1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84140 MCL1 antibody [10F6]. Loading : 5 ug per lane")
![ICC/IF analysis of COS7 cells transiently transfected with MCL1 plasmid using GTX84140 MCL1 antibody [10F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84140/GTX84140_959_ICCIF_w_23061420_632.webp "ICC/IF analysis of COS7 cells transiently transfected with MCL1 plasmid using GTX84140 MCL1 antibody [10F6].")
IHC-P analysis of breast tissue using GTX84140 MCL1 antibody [10F6]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
MCL1 antibody [10F6] - Overexpression Validated
GTX84140
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMCL1
Overview
- SupplierGeneTex
- Product NameMCL1 antibody [10F6] - Overexpression Validated
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10F6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4170
- Target nameMCL1
- Target descriptionMCL1 apoptosis regulator, BCL2 family member
- Target synonymsBCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; induced myeloid leukemia cell differentiation protein Mcl-1; Mcl-1; MCL1, BCL2 family apoptosis regulator; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1 (BCL2-related); TM
- HostMouse
- IsotypeIgG1
- Scientific DescriptionInvolved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203