The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA200543(MCTS1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)

MCTS1 Antibody

Name: MCTS1 Antibody
SKU: CSB-PA200543_C90
Availability: BackOrder

CSB-PA200543

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetMCTS1

Overview

Supplier
Cusabio
Product Name
MCTS1 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID28985
Target name
MCTS1
Target description
MCTS1 re-initiation and release factor
Target synonyms
malignant T-cell amplified sequence 1; malignant T-cell-amplified sequence 1; MCT1; MCT-1; multiple copies in T-cell lymphoma-1; multiple copies T-cell malignancies
Host
Rabbit
Isotype
IgG
Protein IDQ9ULC4
Protein Name
Malignant T-cell-amplified sequence 1
Scientific Description
MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

MCTS1 Antibody

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Overview

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