WB analysis of human liver lysate using GTX89355 MDM2 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human liver lysate using GTX89355 MDM2 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
MDM2 antibody, Internal
GTX89355
Overview
- SupplierGeneTex
- Product NameMDM2 antibody, Internal
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to recognize isoform MDM2 (NP_002383.2) only.
- Application Supplier NoteWB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID4193
- Target nameMDM2
- Target descriptionMDM2 proto-oncogene
- Target synonymsACTFS; double minute 2, human homolog of; p53-binding protein; E3 ubiquitin-protein ligase Mdm2; hdm2; HDMX; LSKB; MDM2 oncogene, E3 ubiquitin protein ligase; MDM2 proto-oncogene, E3 ubiquitin protein ligase; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; oncoprotein Mdm2
- HostGoat
- IsotypeIgG
- Protein IDQ00987
- Protein NameE3 ubiquitin-protein ligase Mdm2
- Scientific DescriptionThis gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203