Western Blot analysis of Hela cells using MDM2 Polyclonal Antibody at dilution of 1:2000.
Western Blot analysis of Hela cells using MDM2 Polyclonal Antibody at dilution of 1:2000.
MDM2 Polyclonal Antibody
E-AB-31995
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMDM2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierWB,IHC,IF,ELISA
- CertificationResearch Use Only
- Concentration1 mg/ml
- Scientific DescriptionThis gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
- UNSPSC12352203