MECOM Polyclonal Antibody
RD266123A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetMECOM
Overview
- SupplierReddot Biotech
- Product NameMECOM Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2122
- Target nameMECOM
- Target descriptionMDS1 and EVI1 complex locus
- Target synonymsAML1-EVI-1; AML1-EVI-1 fusion protein; ecotropic virus integration site 1 protein homolog; EVI1; histone-lysine N-methyltransferase MECOM; KMT8E; MDS1; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; MDS1-EVI1; myelodysplasia syndrome-associated protein 1; oncogene EVI1; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203