Melanoma gp100 antibody [8A4]

GeneTex

Melanoma gp100 antibody [8A4]

9

WB: 1:500-1:1000. IHC-P: 1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

8A4

1 mg/ml

Unconjugated

PMEL

premelanosome protein

D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100, melanocyte protein PMEL, melanocyte protein Pmel 17, melanocyte protein mel 17, melanocytes lineage-specific antigen GP100, melanoma-associated ME20 antigen, melanosomal matrix protein17, silver locus protein homolog, silver, mouse, homolog of

Mouse

IgG2b

Melanocyte protein PMEL

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Canine, Human, Monkey, Rat

-20°C or -80°C,2°C to 8°C

12352203