Merestinib

MedChem Express

Merestinib [1206799-15-6]

10

1206799-15-6

Research Use Only

99.99

C30H22F2N6O3

552.53

Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor ( K i =2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC 50 =11 nM), FLT3 (IC 50 =7 nM), AXL (IC 50 =2 nM), MERTK (IC 50 =10 nM), TEK (IC 50 =63 nM), ROS1, DDR1/2 (IC 50 =0.1/7 nM) and MKNK1/2 (IC 50 =7 nM) [1] [2] .

O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3

-20°C,2°C to 8°C

12352200