Merestinib [1206799-15-6]
T3455
CAS Number1206799-15-6
Product group Chemicals
Estimated Purity99.56%
Molecular Weight552.53
Overview
- SupplierTargetMol Chemicals
- Product NameMerestinib [1206799-15-6]
- Delivery Days Customer9
- CAS Number1206799-15-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameMerestinib
- Estimated Purity99.56%
- Molecular FormulaC30H22F2N6O3
- Molecular Weight552.53
- Scientific DescriptionMerestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.
- Shelf life instruction3 years
- SMILESO(C1=C(C=C2C(=C1)C=NN2C)C=3C=NNC3)C4=C(F)C=C(NC(=O)C=5C(=O)N(C(C)=CC5)C6=CC=C(F)C=C6)C=C4
- Storage Instruction-20°C
- UNSPSC12352200
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