Mesothelin antibody [5B2]

GeneTex

Mesothelin antibody [5B2]

9

IHC-P: 1:40. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

5B2

Unconjugated

MSLN

mesothelin

MPF, SMRP, mesothelin, CAK1 antigen, megakaryocyte potentiating factor, pre-pro-megakaryocyte-potentiating factor, soluble MPF mesothelin related protein

Mouse

IgG1

Mesothelin

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

2°C to 8°C

12352203