Western blot analysis of extracts of various cell lines using METAP2 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using METAP2 Polyclonal Antibody at dilution of 1:1000.
METAP2 Polyclonal Antibody
E-AB-62370
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMETAP2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203