IP analysis of 293T cell lysate using GTX33315 METTL3 antibody. Antibody amount : 3microg / 150microg lysate Dilution : 1:1000
IP analysis of 293T cell lysate using GTX33315 METTL3 antibody. Antibody amount : 3microg / 150microg lysate Dilution : 1:1000
METTL3 antibody
GTX33315
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMETTL3
Overview
- SupplierGeneTex
- Product NameMETTL3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:20 - 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID56339
- Target nameMETTL3
- Target descriptionmethyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
- Target synonymsIME4, M6A, MT-A70, Spo8, hMETTL3, N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase catalytic subunit, adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase, mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase, mRNA m(6)A methyltransferase, methyltransferase like 3, methyltransferase-like protein 3
- HostRabbit
- IsotypeIgG
- Protein IDQ86U44
- Protein NameN(6)-adenosine-methyltransferase catalytic subunit METTL3
- Scientific DescriptionThis gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li K, Zhang D, Zhai S, et al. METTL3-METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneurysms. J Cell Commun Signal. 2023,17(3):897-914. doi: 10.1007/s12079-023-00737-yRead this paper
- Chang X, Lv YF, He J, et al. Gene Expression Profile and Prognostic Value of m6A RNA Methylation Regulators in Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2021,8:85-101. doi: 10.2147/JHC.S296438Read this paper
Datasheet
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