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IP analysis of 293T cell lysate using GTX33315 METTL3 antibody. Antibody amount : 3microg / 150microg lysate Dilution : 1:1000
IP analysis of 293T cell lysate using GTX33315 METTL3 antibody. Antibody amount : 3microg / 150microg lysate Dilution : 1:1000
IP analysis of 293T cell lysate using GTX33315 METTL3 antibody. Antibody amount : 3microg / 150microg lysate Dilution : 1:1000

METTL3 antibody

GTX33315
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMETTL3
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Overview

  • Supplier
    GeneTex
  • Product Name
    METTL3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:20 - 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID56339
  • Target name
    METTL3
  • Target description
    methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
  • Target synonyms
    adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; hMETTL3; IME4; M6A; methyltransferase like 3; methyltransferase-like protein 3; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; MT-A70; N6-adenosine-methyltransferase 70 kDa subunit; N6-adenosine-methyltransferase catalytic subunit; Spo8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86U44
  • Protein Name
    N6-adenosine-methyltransferase catalytic subunit
  • Scientific Description
    This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • METTL3-METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneurysms.
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  • Gene Expression Profile and Prognostic Value of m6A RNA Methylation Regulators in Hepatocellular Carcinoma. Chang X et al., 2021, J Hepatocell Carcinoma
    Read more