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METTL3 antibody [N2C2], Internal

GTX105037
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMETTL3
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Overview

  • Supplier
    GeneTex
  • Product Name
    METTL3 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.54 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID56339
  • Target name
    METTL3
  • Target description
    methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
  • Target synonyms
    IME4, M6A, MT-A70, Spo8, hMETTL3, N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase catalytic subunit, adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase, mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase, mRNA m(6)A methyltransferase, methyltransferase like 3, methyltransferase-like protein 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86U44
  • Protein Name
    N(6)-adenosine-methyltransferase catalytic subunit METTL3
  • Scientific Description
    This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chang X, Lv YF, He J, et al. Gene Expression Profile and Prognostic Value of m6A RNA Methylation Regulators in Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2021,8:85-101. doi: 10.2147/JHC.S296438
    Read this paper
  • Liang S, Guan H, Lin X, et al. METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway. Oncol Lett. 2020,19(4):3197-3204. doi: 10.3892/ol.2020.11425
    Read this paper