mGluR1 antibody

GeneTex

mGluR1 antibody

9

WB: 1:500-2000. IHC-P: 1:400-800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

GRM1

glutamate metabotropic receptor 1

glutamate receptor, metabotropic 1; GPRC1A; metabotropic glutamate receptor 1; MGLU1; MGLUR1; PPP1R85; protein phosphatase 1, regulatory subunit 85; SCA44; SCAR13

Rabbit

IgG

Metabotropic glutamate receptor 1

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

-20°C or -80°C,2°C to 8°C

12352203