WB analysis of HepG2 cell lysate using GTX64402 MGMT antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of HepG2 cell lysate using GTX64402 MGMT antibody. Dilution : 1:1000 Loading : 25microg per lane
MGMT antibody
GTX64402
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetMGMT
Overview
- SupplierGeneTex
- Product NameMGMT antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4255
- Target nameMGMT
- Target descriptionO-6-methylguanine-DNA methyltransferase
- Target synonyms6-O-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase
- HostRabbit
- IsotypeIgG
- Protein IDP16455
- Protein NameMethylated-DNA--protein-cysteine methyltransferase
- Scientific DescriptionAlkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203