Mineralocorticoid Receptor antibody

GeneTex

Mineralocorticoid Receptor antibody

9

Superfamily members of NR3C2 are not reactive to this antibody.

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

NR3C2

nuclear receptor subfamily 3 group C member 2

aldosterone receptor; MCR; mineralocorticoid receptor; mineralocorticoid receptor 1; mineralocorticoid receptor 2; mineralocorticoid receptor delta; MLR; MR; NR3C2VIT; nuclear receptor subfamily 3, group C, member 2 variant 3

Rabbit

IgG

This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203