MMP11 antibody
GTX11610
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMMP11
Overview
- SupplierGeneTex
- Product NameMMP11 antibody
- Delivery Days Customer9
- Antibody SpecificityReacts with reduced and non-reduced MMP-11. Recognizes the pro-form of MMP-11 at 58 kDa but not the active form at 45 kDa.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4320
- Target nameMMP11
- Target descriptionmatrix metallopeptidase 11
- Target synonymsmatrix metallopeptidase 11 (stromelysin 3); SL-3; ST3; STMY3; stromelysin III; stromelysin-3
- HostRabbit
- IsotypeIgG
- Protein IDP24347
- Protein NameStromelysin-3
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMPs, this enzyme cleaves alpha 1 proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203