MMP11 antibody

GeneTex

MMP11 antibody

9

Reacts with reduced and non-reduced MMP-11. Recognizes active forms of MMP-11. By immunoblotting, the antibody reacts with bands at 58 kDa and 45 kDa.

WB: 1:1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MMP11

matrix metallopeptidase 11

matrix metallopeptidase 11 (stromelysin 3); SL-3; ST3; STMY3; stromelysin III; stromelysin-3

Rabbit

IgG

Stromelysin-3

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMPs, this enzyme cleaves alpha 1 proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Human

-20°C or -80°C,2°C to 8°C

12352203