MMP13 antibody [12E10]

GeneTex

MMP13 antibody [12E10]

9

This antibody recognizes human MMP-13 in western blot without cross reactivity with other human MMPs.

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

200 ug/ml

Unconjugated

MMP13

matrix metallopeptidase 13

CLG3; collagenase 3; MANDP1; matrix metalloproteinase 13 (collagenase 3); MDST; MMP-13

Mouse

IgG1

Collagenase 3

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203