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WB analysis of various sample lysates using GTX55707 MMP13 antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX55707 MMP13 antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX55707 MMP13 antibody. Dilution : 1:1000 Loading : 25microg per lane

MMP13 antibody

GTX55707
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMMP13
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Overview

  • Supplier
    GeneTex
  • Product Name
    MMP13 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4322
  • Target name
    MMP13
  • Target description
    matrix metallopeptidase 13
  • Target synonyms
    CLG3; collagenase 3; MANDP1; matrix metalloproteinase 13 (collagenase 3); MDST; MMP-13
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP45452
  • Protein Name
    Collagenase 3
  • Scientific Description
    This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats. Sun Q et al., 2021 May 28, Arthritis Res Ther
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