ProductsBack/MMP2 antibody [MMP2/1501]

Analysis of Protein Array containing more than 19,000 full-length human proteins using MMP2 Mouse Monoclonal Antibody (MMP2/1501). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

MMP2 antibody [MMP2/1501]

GTX34845

ApplicationsWestern Blot, Other Application

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Product group Antibodies

TargetMMP2

Overview

Supplier
GeneTex
Product Name
MMP2 antibody [MMP2/1501]
Delivery Days Customer
9
Application Supplier Note
WB: 1-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, Other Application
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
MMP2/1501
Concentration
0.2 mg/ml
Conjugate
Unconjugated
Gene ID4313
Target name
MMP2
Target description
matrix metallopeptidase 2
Target synonyms
72 kDa type IV collagenase; CLG4; CLG4A; collagenase type IV-A; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloproteinase-2; matrix metalloproteinase-II; MMP-2; MMP-II; MONA; neutrophil gelatinase; TBE-1
Host
Mouse
Isotype
IgG1
Protein IDP08253
Protein Name
72 kDa type IV collagenase
Scientific Description
This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

MMP2 antibody [MMP2/1501]

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