MMP20 Polyclonal Antibody

Reddot Biotech

MMP20 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.1 mg/ml

Unconjugated

MMP20

matrix metallopeptidase 20

AI2A2; enamel metalloproteinase; matrix metalloproteinase 20 (enamelysin); matrix metalloproteinase-20; MMP-20

Rabbit

IgG

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.

Human, Mouse

-20°C

12352203