WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MPZ (Lane 2) using GTX81135 MPZ antibody, C-term.
WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MPZ (Lane 2) using GTX81135 MPZ antibody, C-term.
MPZ antibody, C-term
GTX81135
Overview
- SupplierGeneTex
- Product NameMPZ antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:50-1:100. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Gene ID4359
- Target nameMPZ
- Target descriptionmyelin protein zero
- Target synonymsCharcot-Marie-Tooth neuropathy 1B; CHM; CHN2; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; DSS; HMSNIB; MPP; myelin peripheral protein; myelin protein P0; P0
- Protein IDP25189
- Protein NameMyelin protein P0
- Scientific DescriptionThis gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203