MRL-871 [1392809-08-3]

TargetMol Chemicals

MRL-871 [1392809-08-3]

72

1392809-08-3

Research Use Only

MRL-871

C22H12ClF3N2O3

444.79

MRL-871 (compound 3) is a potent inverse agonist of the isotretinoin receptor-related orphan receptor gammat (RORgammat) with an IC50 of 264 nM. Possessing a specific isoxazole chemotype, MRL-871 effectively reduces IL-17a mRNA production in EL4 cells.

3 years

C(=O)(N1N=C(C=2C1=CC=CC2)C3=CC=C(C(O)=O)C=C3)C4=C(C(F)(F)F)C=CC=C4Cl

-20°C

12352200