MSH3 antibody [HL2546]

GeneTex

MSH3 antibody [HL2546]

9

WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

HL2546

1 mg/ml

Unconjugated

MSH3

mutS homolog 3

divergent upstream protein; DNA mismatch repair protein Msh3; DUP; epididymis secretory sperm binding protein; FAP4; hMSH3; mismatch repair protein 1; MRP1

Rabbit

IgG

DNA mismatch repair protein Msh3

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203