ICC/IF analysis of HeLa cells using MSH6 antibody at a dilution of 1:100.
ICC/IF analysis of HeLa cells using MSH6 antibody at a dilution of 1:100.
MSH6 antibody [3E1-B11-F12]
GTX49251
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetMSH6
Overview
- SupplierGeneTex
- Product NameMSH6 antibody [3E1-B11-F12]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3E1-B11-F12
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2956
- Target nameMSH6
- Target descriptionmutS homolog 6
- Target synonymsDNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; HNPCC5; HSAP; MMRCS3; mutS protein homolog 6; mutS-alpha 160 kDa subunit; p160; sperm-associated protein
- HostMouse
- IsotypeIgG2a
- Protein IDP52701
- Protein NameDNA mismatch repair protein Msh6
- Scientific DescriptionThis gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203