Bio-Connect

mTOR antibody [C3], C-term

GTX101557
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMTOR
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    mTOR antibody [C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.05 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2475
  • Target name
    MTOR
  • Target description
    mechanistic target of rapamycin kinase
  • Target synonyms
    FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS, serine/threonine-protein kinase mTOR, FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP-rapamycin associated protein, FKBP12-rapamycin complex-associated protein 1, mammalian target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2, rapamycin target protein 1, tyrosine-protein kinase mTOR
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP42345
  • Protein Name
    Serine/threonine-protein kinase mTOR
  • Scientific Description
    The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dernovics Á, Seprényi G, Rázga Z, et al. Phenol-Soluble Modulin α3 Stimulates Autophagy in HaCaT Keratinocytes. Biomedicines. 2023,11(11). doi: 10.3390/biomedicines11113018
    Read this paper
  • Wang J, Hua G, Chen J, et al. Epigenetic mechanism of Gtl2-miRNAs causes the primitive sheep characteristics found in purebred Merino sheep. Cell Biosci. 2023,13(1):190. doi: 10.1186/s13578-023-01142-z
    Read this paper
  • Tian X, Wei Y, Hou R, et al. Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization. Chin Med. 2023,18(1):79. doi: 10.1186/s13020-023-00787-9
    Read this paper
  • Duan S, Qin N, Pi J, et al. Antagonizing apolipoprotein J chaperone promotes proteasomal degradation of mTOR and relieves hepatic lipid deposition. Hepatology. 2023,78(4):1182-1199. doi: 10.1097/HEP.0000000000000185
    Read this paper
  • Li M, Zhang W, Wang Y, et al. DDTC Suppresses Ovarian Cancer Development via the PI3K/AKT/mTOR Signaling Pathway. Dis Markers. 2022,2022:1941077. doi: 10.1155/2022/1941077
    Read this paper
  • Ma YX, Jiao K, Wan QQ, et al. Silicified collagen scaffold induces semaphorin 3A secretion by sensory nerves to improve in-situ bone regeneration. Bioact Mater. 2022,9:475-490. doi: 10.1016/j.bioactmat.2021.07.016
    Read this paper
  • Hashikawa-Hobara N, Otsuka A, Okujima C, et al. CGRP overexpression does not alter depression-like behavior in mice. PeerJ. 2021,9:e11720. doi: 10.7717/peerj.11720
    Read this paper
  • Lee TY, Lu WJ, Changou CA, et al. Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism. Autophagy. 2021,17(12):4141-4158. doi: 10.1080/15548627.2021.1904495
    Read this paper
  • Cheung CHY, Hsu CL, Lin TY, et al. ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer. J Biomed Sci. 2020,27(1):75. doi: 10.1186/s12929-020-00668-5
    Read this paper
  • Li J, Ma J, Tian Y, et al. Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. J Ethnopharmacol. 2020,257:112796. doi: 10.1016/j.jep.2020.112796
    Read this paper