The data was published in the journal PLoS One in 2012. PMID: 22235261
The data was published in the journal PLoS One in 2012. PMID: 22235261
MURF1 antibody
GTX24125
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat, Zebra Fish
TargetTRIM63
Overview
- SupplierGeneTex
- Product NameMURF1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:100 - 1:2000. IHC-P: 1.25microg/ml. IHC: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID84676
- Target nameTRIM63
- Target descriptiontripartite motif containing 63
- Target synonymsE3 ubiquitin-protein ligase TRIM63; IRF; iris ring finger protein; MURF1; MURF2; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF28; SMRZ; striated muscle RING zinc finger protein; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif-containing protein 63
- HostGoat
- IsotypeIgG
- Protein IDQ969Q1
- Protein NameE3 ubiquitin-protein ligase TRIM63
- Scientific DescriptionThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
- ReactivityHuman, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Cunha JE et al., 2019 Apr 24, Sci RepRead more
- Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle. Rowan SL et al., 2012, PLoS OneRead more
- The zebrafish runzel muscular dystrophy is linked to the titin gene. Steffen LS et al., 2007 Sep 15, Dev BiolRead more