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The data was published in the journal PLoS One in 2012. PMID: 22235261
The data was published in the journal PLoS One in 2012. PMID: 22235261
The data was published in the journal PLoS One in 2012. PMID: 22235261

MURF1 antibody

GTX24125
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat, Zebra Fish
TargetTRIM63
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Overview

  • Supplier
    GeneTex
  • Product Name
    MURF1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:100 - 1:2000. IHC-P: 1.25microg/ml. IHC: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID84676
  • Target name
    TRIM63
  • Target description
    tripartite motif containing 63
  • Target synonyms
    CMH31, IRF, MURF1, MURF2, RNF28, SMRZ, E3 ubiquitin-protein ligase TRIM63, RING-type E3 ubiquitin transferase TRIM63, iris ring finger protein, muscle specific ring finger protein 2, muscle-specific RING finger protein 1, ring finger protein 28, striated muscle RING zinc finger protein, tripartite motif containing 63, E3 ubiquitin protein ligase, tripartite motif-containing protein 63
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDQ969Q1
  • Protein Name
    E3 ubiquitin-protein ligase TRIM63
  • Scientific Description
    This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
  • Reactivity
    Human, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cunha JE, Barbosa GM, Castro PATS, et al. Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Sci Rep. 2019,9(1):6366. doi: 10.1038/s41598-019-42546-7
    Read this paper
  • Rowan SL, Rygiel K, Purves-Smith FM, et al. Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle. PLoS One. 2012,7(1):e29082. doi: 10.1371/journal.pone.0029082
    Read this paper
  • Steffen LS, Guyon JR, Vogel ED, et al. The zebrafish runzel muscular dystrophy is linked to the titin gene. Dev Biol. 2007,309(2):180-92.
    Read this paper