Muscleblind-like 1 antibody, C-term

GeneTex

Muscleblind-like 1 antibody, C-term

7

This antibody is expected to recognize the reported isoforms (NP_066368.2; NP_997175.1; NP_997176.1; NP_997177.1; NP_997178.1; NP_997179.1)

WB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

MBNL1

muscleblind like splicing regulator 1

EXP; MBNL; muscleblind-like; muscleblind-like protein 1; triplet-expansion RNA-binding protein

Goat

IgG

Muscleblind-like protein 1

This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203