Myotilin antibody
GTX109905
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMYOT
Overview
- SupplierGeneTex
- Product NameMyotilin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9499
- Target nameMYOT
- Target descriptionmyotilin
- Target synonyms57 kDa cytoskeletal protein; LGMD1; LGMD1A; MFM3; myofibrillar titin-like Ig domains protein; myotilin; titin immunoglobulin domain protein (myotilin); TTID; TTOD
- HostRabbit
- IsotypeIgG
- Protein IDQ9UBF9
- Protein NameMyotilin
- Scientific DescriptionThis gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training. Roberts MD et al., 2018, PeerJRead more