IHC-P analysis of human skeletal muscle tissue using GTX01881 Myotilin antibody [RSO34]. Note sarcoplasmic staining of normal muscle fibers (A) and presence of protein aggregates (B).
IHC-P analysis of human skeletal muscle tissue using GTX01881 Myotilin antibody [RSO34]. Note sarcoplasmic staining of normal muscle fibers (A) and presence of protein aggregates (B).
Myotilin antibody [RSO34]
GTX01881
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMYOT
Overview
- SupplierGeneTex
- Product NameMyotilin antibody [RSO34]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRSO34
- ConjugateUnconjugated
- Gene ID9499
- Target nameMYOT
- Target descriptionmyotilin
- Target synonyms57 kDa cytoskeletal protein; LGMD1; LGMD1A; MFM3; myofibrillar titin-like Ig domains protein; myotilin; titin immunoglobulin domain protein (myotilin); TTID; TTOD
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203