Western blot analysis of extracts from Rat and Mouse brain tissue using NAC1 Antibody.
Western blot analysis of extracts from Rat and Mouse brain tissue using NAC1 Antibody.
NACC1 Antibody
CSB-PA283286
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetNACC1
Overview
- SupplierCusabio
- Product NameNACC1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID112939
- Target nameNACC1
- Target descriptionnucleus accumbens associated 1
- Target synonymsBEN domain containing 8; BEND8; BTB/POZ domain-containing protein 14B; BTBD14B; BTBD30; NAC1; NAC-1; NECFM; nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 1; transcriptional repressor NAC1
- HostRabbit
- IsotypeIgG
- Protein IDQ96RE7
- Protein NameNucleus accumbens-associated protein 1
- Scientific DescriptionFunctions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival. Nakayama K., Nakayama N., Davidson B.,et al. Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor. Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203