NAE1 Antibody

Cusabio

NAE1 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

NAE1

NEDD8 activating enzyme E1 subunit 1

A-116A10.1, APPBP1, HPP1, NEDFIH, ula-1, NEDD8-activating enzyme E1 regulatory subunit, APP-BP1, NEDD8-activating enzyme E1 subunit, amyloid beta precursor protein binding protein 1, 59kDa, amyloid beta precursor protein-binding protein 1, 59 kDa, amyloid beta precursor protein-binding protein 1, 59kD, amyloid protein-binding protein 1, proto-oncogene protein 1, protooncogene protein 1

Rabbit

IgG

NEDD8-activating enzyme E1 regulatory subunit

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimers disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C or -80°C

41116161