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NARFL antibody

Research Use Only
GTX116764
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCIAO3
Price on request
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ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    NARFL antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.72 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64428
  • Target name
    CIAO3
  • Target description
    cytosolic iron-sulfur assembly component 3
  • Target synonyms
    cytosolic Fe-S cluster assembly factor NARFL; cytosolic iron-sulfur assembly component 3; HPRN; IOP1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; NAR1; NARFL; nuclear prelamin A recognition factor like; PRN; protein related to Narf
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy. Wu H et al., 2020 Sep, Redox Biol
    Read more
  • Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Ast T et al., 2019 May 30, Cell
    Read more