NDUFV1 antibody

GeneTex

NDUFV1 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

NDUFV1

NADH:ubiquinone oxidoreductase core subunit V1

CI-51K; CI51KD; complex I 51 kda subunit; complex I 51kDa subunit; complex I, mitochondrial respiratory chain; MC1DN4; mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1; mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit; NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; NADH-ubiquinone oxidoreductase 51 kDa subunit; UQOR1

Rabbit

IgG

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinsons disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203