Necrosulfonamide [1360614-48-7]
M9062
CAS Number1360614-48-7
Product group Chemicals
Estimated Puritymore then99%
Molecular Weight461.47
Overview
- SupplierAbMole BioScience
- Product NameNecrosulfonamide [1360614-48-7]
- Delivery Days Customer7
- CAS Number1360614-48-7
- CertificationResearch Use Only
- Estimated Puritymore then99%
- Molecular FormulaC18H15N5O6S2
- Molecular Weight461.47
- Scientific DescriptionNecrosulfonamide is a necroptosis inhibitor which selectively targeting the mixed lineage kinase domain-like protein (MLKL) with IC50 value of 124 nM in human HT-29. Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors.
- SMILESCOC1=C(N[S](=O)(=O)C2=CC=C(NC(=O)\C=C\C3=CC=C(S3)[N+]([O-])=O)C=C2)N=CC=N1
- Storage Instruction-20°C
- UNSPSC12161507
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