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Necrosulfonamide

M9062
AbMole BioScience
CAS Number1360614-48-7
Product group Chemicals
Molecular Weight461.47
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Necrosulfonamide
  • Delivery Days Customer
    9
  • CAS Number
    1360614-48-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C18H15N5O6S2
  • Molecular Weight
    461.47
  • Scientific Description
    Necrosulfonamide is a necroptosis inhibitor which selectively targeting the mixed lineage kinase domain-like protein (MLKL) with IC50 value of 124 nM in human HT-29. Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors.
  • SMILES
    COC1=C(N[S](=O)(=O)C2=CC=C(NC(=O)\C=C\C3=CC=C(S3)[N+]([O-])=O)C=C2)N=CC=N1
  • UNSPSC
    12352200

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