Necrosulfonamide [1360614-48-7]
T6904
CAS Number1360614-48-7
Product group Chemicals
Estimated Purity99.49%
Molecular Weight461.47
Overview
- SupplierTargetMol Chemicals
- Product NameNecrosulfonamide
- Delivery Days Customer4
- CAS Number1360614-48-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameNecrosulfonamide
- Estimated Purity99.49%
- Molecular FormulaC18H15N5O6S2
- Molecular Weight461.47
- Scientific Description(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis.
- Shelf life instruction3 years
- SMILESCOc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1
- Storage Instruction-20°C
- UNSPSC12352200
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