NECTIN4 Polyclonal Antibody

Reddot Biotech

NECTIN4 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

NECTIN4

nectin cell adhesion molecule 4

EDSS1; Ig superfamily receptor LNIR; LNIR; nectin 4; nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; PRR4; PVRL4

Rabbit

IgG

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Human, Mouse

-20°C

12352203